Pirkko J Pussinen Selected Research

Periodontitis

11/2022	Salivary IgA antibody to malondialdehyde-acetaldehyde associates with mild periodontal pocket depth.
11/2022	Common complement factor H polymorphisms are linked with periodontitis in elderly patients.
1/2022	Periodontitis and cardiometabolic disorders: The role of lipopolysaccharide and endotoxemia.
1/2022	Periodontal conditions and incident dementia: A nationwide Swedish cohort study.
8/2020	Immunological and Microbiological Profiling of Cumulative Risk Score for Periodontitis.
1/2020	Serum lipopolysaccharide neutralizing capacity in ischemic stroke.
6/2019	Saliva and Serum Immune Responses in Apical Periodontitis.
1/2019	Smoking confounds the periodontal diagnostics using saliva biomarkers.
10/2018	Mediators between oral dysbiosis and cardiovascular diseases.
10/2018	Cumulative use of salivary markers with an adaptive design improves detection of periodontal disease over fixed biomarker thresholds.

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Pirkko J Pussinen Research Topics

Disease

44	Periodontitis 11/2022 - 07/2003
19	Inflammation (Inflammations) 01/2022 - 01/2007
13	Infections 06/2019 - 09/2003
12	Atherosclerosis 11/2022 - 10/2004
10	Cardiovascular Diseases (Cardiovascular Disease) 01/2020 - 10/2004
9	Coronary Artery Disease (Coronary Atherosclerosis) 11/2022 - 05/2014
8	Periodontal Diseases (Periodontal Disease) 11/2022 - 01/2006
7	Alveolar Bone Loss 11/2022 - 02/2009
7	Stroke (Strokes) 11/2021 - 09/2004
6	Endotoxemia 01/2022 - 01/2007
6	Acute Coronary Syndrome 01/2018 - 07/2013
5	Hemorrhage 01/2021 - 11/2011
5	Atherosclerotic Plaque (Atheroma) 01/2018 - 12/2007
4	Periodontal Pocket (Periodontal Pockets) 11/2022 - 06/2010
4	Myocardial Infarction 01/2017 - 10/2004
3	Ischemic Stroke 01/2020 - 11/2016
3	Rupture 01/2018 - 07/2014
3	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2014 - 09/2009
3	Metabolic Syndrome (Dysmetabolic Syndrome X) 08/2011 - 09/2009
3	Coronary Disease (Coronary Heart Disease) 12/2007 - 07/2003
2	Peri-Implantitis 02/2016 - 02/2011
2	Chronic Periodontitis 01/2016 - 01/2014
2	Obesity 04/2015 - 08/2011
2	Infarction (Infarctions) 08/2012 - 10/2006
2	Unstable Angina 08/2012 - 10/2006
2	Kidney Diseases (Kidney Disease) 08/2011 - 09/2009
2	Necrosis 11/2009 - 01/2009
1	Dementia (Dementias) 01/2022
1	Thrombosis (Thrombus) 11/2021
1	Thromboembolism 11/2021
1	Periapical Periodontitis (Apical Periodontitis) 06/2019
1	Tooth Loss 10/2018
1	Dysbiosis 10/2018

Drug/Important Bio-Agent (IBA)

20	Biomarkers (Surrogate Marker)IBA 01/2021 - 01/2007
18	Matrix Metalloproteinases (MMPs)IBA 01/2018 - 01/2007
15	AntibodiesIBA 11/2022 - 07/2003
14	LipopolysaccharidesIBA 01/2022 - 11/2004
10	Immunoglobulin A (IgA)IBA 11/2022 - 09/2004
10	Immunoglobulin G (IgG)IBA 06/2019 - 07/2003
8	Lipoproteins (Lipoprotein)IBA 11/2021 - 10/2004
8	Tissue Inhibitor of Metalloproteinase-1IBA 01/2019 - 12/2007
7	Matrix Metalloproteinase 8 (Neutrophil Collagenase)IBA 01/2018 - 01/2011
7	CholesterolIBA 07/2013 - 01/2004
5	Tuberculin (PPD)IBA 11/2022 - 11/2009
5	oxidized low density lipoproteinIBA 11/2022 - 11/2004
5	HDL LipoproteinsIBA 01/2021 - 01/2004
5	Peroxidase (Myeloperoxidase)IBA 10/2018 - 01/2016
5	EnzymesIBA 01/2016 - 11/2009
4	LipidsIBA 10/2018 - 08/2009
4	CytokinesIBA 01/2017 - 01/2007
4	C-Reactive ProteinIBA 01/2017 - 11/2005
4	Doxycycline (Periostat)FDA LinkGeneric 04/2015 - 02/2011
4	HDL CholesterolIBA 07/2013 - 11/2005
4	EndotoxinsIBA 06/2013 - 06/2007
3	EpitopesIBA 11/2022 - 05/2015
3	Biological ProductsIBA 01/2022 - 10/2013
3	Fatty Acids (Saturated Fatty Acids)IBA 01/2021 - 08/2009
3	Immunoglobulins (Immunoglobulin)IBA 06/2019 - 02/2009
3	Matrix Metalloproteinase 1 (Interstitial Collagenase)IBA 01/2018 - 01/2017
3	LDL Lipoproteins (beta Lipoproteins)IBA 05/2015 - 11/2005
3	ApolipoproteinsIBA 10/2013 - 02/2008
3	Clarithromycin (Biaxin)FDA LinkGeneric 08/2012 - 10/2006
3	Triglycerides (Triacylglycerol)IBA 09/2009 - 11/2005
2	Malondialdehyde (Propanedial)IBA 11/2022 - 05/2015
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2021 - 07/2007
2	Lipopolysaccharide ReceptorsIBA 01/2020 - 01/2007
2	Phospholipid Transfer ProteinsIBA 01/2020 - 09/2011
2	lipopolysaccharide-binding proteinIBA 01/2020 - 01/2007
2	Interleukin-8 (Interleukin 8)IBA 10/2018 - 01/2009
2	Peptide Hydrolases (Proteases)FDA Link 01/2017 - 07/2014
2	Immunoglobulin M (IgM)IBA 11/2015 - 05/2015
2	Interleukin-10 (Interleukin 10)IBA 05/2015 - 01/2009
2	Apolipoproteins E (ApoE)IBA 10/2013 - 09/2011
2	Interleukin-6 (Interleukin 6)IBA 05/2013 - 11/2009
2	Collagen Type I (Type I Collagen)IBA 01/2013 - 06/2010
2	Serum Amyloid A Protein (Serum Amyloid A)IBA 09/2011 - 08/2009
2	Indicators and Reagents (Reagents)IBA 02/2011 - 02/2009
2	Glucose (Dextrose)FDA LinkGeneric 10/2009 - 09/2009
2	LDL CholesterolIBA 11/2005 - 11/2005
1	Chaperonin 60IBA 11/2022
1	AcetaldehydeIBA 11/2022
1	S100A12 ProteinIBA 11/2022
1	Complement Factor H (Factor H)IBA 11/2022
1	Complement System Proteins (Complement)IBA 11/2022
1	N,N'-diphenyl-4-phenylenediamineIBA 01/2022
1	Branched-Chain Amino AcidsIBA 01/2021
1	Glycoproteins (Glycoprotein)IBA 01/2021
1	Apolipoproteins B (ApoB)IBA 01/2020
1	Proteins (Proteins, Gene)FDA Link 01/2020
1	lipoprotein A-IIBA 01/2020
1	Bacterial AntigensIBA 06/2019
1	Virulence Factors (Pathogenicity Factors)IBA 10/2018
1	Lymphotoxin-alpha (Lymphotoxin)IBA 10/2018
1	Tissue Inhibitor of MetalloproteinasesIBA 01/2018
1	lipopolysaccharide AIBA 08/2017
1	CollagenIBA 01/2017

Therapy/Procedure

4	Aftercare (After-Treatment) 01/2017 - 11/2004
3	Oral Diagnosis (Oral Examination) 06/2019 - 12/2013
2	Therapeutics 08/2014 - 10/2006
1	Ligation 01/2017